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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LATS1 All Species: 8.79
Human Site: S336 Identified Species: 13.81
UniProt: O95835 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95835 NP_004681.1 1130 126870 S336 P I I M Q S S S K F N F P S G
Chimpanzee Pan troglodytes XP_001173355 1130 126853 S336 P I I M Q S S S K F N F P S G
Rhesus Macaque Macaca mulatta XP_001090321 809 89257 A88 F G A D G P A A L E E V P R P
Dog Lupus familis XP_534537 1097 121903 L323 P T G T P T G L Y M P H T H H
Cat Felis silvestris
Mouse Mus musculus Q8BYR2 1129 126167 T335 Q P I I M Q S T S K F N F T P
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506215 1121 123969 K327 I M P S S N S K F N F P P G R
Chicken Gallus gallus XP_419666 1136 127431 K342 M Q S S A N S K F S F P S G R
Frog Xenopus laevis NP_001087838 1118 125984 N331 P I I M Q T S N T K F G Y S G
Zebra Danio Brachydanio rerio NP_001018346 1068 120780 Q322 G M N S G A R Q P P P P P Y S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VA38 1105 122470 S325 Q Q S D Y R K S P S S G I Y S
Honey Bee Apis mellifera XP_395146 1137 124999 I372 S P I T V S A I S P N T Q A S
Nematode Worm Caenorhab. elegans Q2L6W9 476 55529
Sea Urchin Strong. purpuratus XP_795100 1199 133231 S412 N V Q H G S T S K E Q H R S S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53894 756 86927 Y35 Q H Q Q Q Q Q Y A N E M N P Y
Red Bread Mold Neurospora crassa P38679 598 67999
Conservation
Percent
Protein Identity: 100 99.6 35.8 50.9 N.A. 92.8 N.A. N.A. 80.8 85.2 74.7 63.1 N.A. 38.6 40.2 20.7 38
Protein Similarity: 100 99.8 44.7 63.4 N.A. 96.7 N.A. N.A. 87.1 92.1 83.4 73.7 N.A. 50.2 52.6 29.6 51.9
P-Site Identity: 100 100 6.6 6.6 N.A. 13.3 N.A. N.A. 13.3 6.6 53.3 6.6 N.A. 6.6 20 0 26.6
P-Site Similarity: 100 100 20 13.3 N.A. 33.3 N.A. N.A. 26.6 13.3 66.6 20 N.A. 13.3 33.3 0 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. 28 24.4
Protein Similarity: N.A. N.A. N.A. N.A. 42.3 35.5
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 0
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 0 7 7 14 7 7 0 0 0 0 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 14 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 14 14 0 0 0 0 % E
% Phe: 7 0 0 0 0 0 0 0 14 14 27 14 7 0 0 % F
% Gly: 7 7 7 0 20 0 7 0 0 0 0 14 0 14 20 % G
% His: 0 7 0 7 0 0 0 0 0 0 0 14 0 7 7 % H
% Ile: 7 20 34 7 0 0 0 7 0 0 0 0 7 0 0 % I
% Lys: 0 0 0 0 0 0 7 14 20 14 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 7 7 0 0 0 0 0 0 % L
% Met: 7 14 0 20 7 0 0 0 0 7 0 7 0 0 0 % M
% Asn: 7 0 7 0 0 14 0 7 0 14 20 7 7 0 0 % N
% Pro: 27 14 7 0 7 7 0 0 14 14 14 20 34 7 14 % P
% Gln: 20 14 14 7 27 14 7 7 0 0 7 0 7 0 0 % Q
% Arg: 0 0 0 0 0 7 7 0 0 0 0 0 7 7 14 % R
% Ser: 7 0 14 20 7 27 40 27 14 14 7 0 7 27 27 % S
% Thr: 0 7 0 14 0 14 7 7 7 0 0 7 7 7 0 % T
% Val: 0 7 0 0 7 0 0 0 0 0 0 7 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 7 0 0 7 7 0 0 0 7 14 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _